SCHEMBL2020228

SCHEMBL2020228

CC(C)(c1ccc(C(C)(C)c2cccc(N)c2N)cc1)c1cccc(N)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.43
CYP3A4 P08684 6/20 0.37
TSHR P16473 3/20 0.37
PIK3CA P42336 1/20 0.37
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
AR P10275 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
HTR6 P50406 1/20 0.34
ESRRG P62508 1/20 0.34
SLC6A3 Q01959 1/20 0.34
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 2/20 0.33
CA2 P00918 1/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30606647 0.92 CYP3A4 (0.41) CD44CYP3A4TSHRPIK3CAESR1
SCHEMBL4409081 0.92 CYP3A4 (0.41) CD44CYP3A4TSHRPIK3CAESR1
SCHEMBL8512559 0.89 CD44 (0.48) CD44CYP3A4TSHRPIK3CAHPGD
SCHEMBL2034203 0.82 CYP3A4 (0.41) CYP3A4TSHRPIK3CAESR1ESR2
SCHEMBL24549530 0.80 ESR1 (0.45) CYP3A4ESR1ESR2ALDH1A1MAPT
SCHEMBL6028201 0.79 CD44 (0.48) CD44CYP3A4TSHRPIK3CAHPGD
SCHEMBL10392513 0.77 S1PR1 (0.39) CYP3A4TSHRESR1ESR2HPGD
SCHEMBL29919506 0.77 CD44 (0.41) CD44CYP3A4TSHRPIK3CAHPGD
SCHEMBL3751989 0.76 CYP3A4 (0.45) CYP3A4ESR1ESR2ALDH1A1TDP1
Hydrochloric Acid SCHEMBL3291595 0.74 CYP3A4 (0.43) CYP3A4ESR1ESR2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519040-B2 Ionic organic compound, production method thereof, hydrogelling agent composed of the ionic organic compound, hydrogel containing same, methanol gelling agent, methanol gel containing same, and carbon nanotube dispersant NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2013-08-27 US disclosed
US-20110178218-A1 IONIC ORGANIC COMPOUND, PRODUCTION METHOD THEREOF, HYDROGELLING AGENT COMPOSED OF THE IONIC ORGANIC COMPOUND, HYDROGEL CONTAINING SAME, METHANOL GELLING AGENT, METHANOL GEL CONTAINING SAME, AND CARBON NANOTUBE DISPERSANT National Institute of Avanced Industrial Science and Technology (JP) 2011-07-21 US disclosed
EP-2330143-A1 IONIC ORGANIC COMPOUND, PRODUCTION METHOD THEREOF, HYDROGELLING AGENT COMPOSED OF THE IONIC ORGANIC COMPOUND, HYDROGEL CONTAINING SAME, METHANOL GELLING AGENT, METHANOL GEL CONTAINING SAME, AND CARBON NANOTUBE DISPERSANT National Institute of Advanced Industrial Science And Technology (JP) 2011-06-08 EP disclosed