Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657596 | 0.92 | ESR1 (0.49) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL20202508 | 0.89 | ESR1 (0.46) | ESR1ESR2KMT2AMEN1MAPT | |
| SCHEMBL14580094 | 0.89 | ESR1 (0.50) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL20202509 | 0.89 | ESR1 (0.42) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL20202507 | 0.89 | ESR1 (0.42) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL16979793 | 0.84 | ESR1 (0.45) | ESR1ESR2TDP1NPSR1KMT2A | |
| SCHEMBL12021689 | 0.81 | ESR1 (0.56) | ESR1ESR2GAAKMT2AMEN1 | |
| SCHEMBL22651381 | 0.81 | ESR1 (0.56) | ESR1ESR2GAAKMT2AMEN1 | |
| SCHEMBL20202506 | 0.81 | KMT2A (0.38) | ESR1ESR2TDP1GAAKMT2A | |
| SCHEMBL22048120 | 0.80 | ESR1 (0.50) | ESR1ESR2GAANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148538-A1 | POLYARYLATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-05-31 | — | — | US | disclosed |