Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15985745 | 1.00 | HSD17B10 (0.47) | HSD17B10ALDH1A1HTTGAASIGMAR1 | |
| SCHEMBL22815172 | 1.00 | HSD17B10 (0.47) | HSD17B10ALDH1A1HTTGAASIGMAR1 | |
| SCHEMBL27255807 | 0.98 | HSD17B10 (0.48) | HSD17B10ALDH1A1HTTGAASIGMAR1 | |
| SCHEMBL13698376 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAASLC6A9 | |
| SCHEMBL21764407 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAASLC6A9 | |
| SCHEMBL16220530 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAASLC6A9 | |
| SCHEMBL12344753 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAASLC6A9 | |
| SCHEMBL19766443 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAASLC6A9 | |
| SCHEMBL25752709 | 0.93 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAASLC6A9 | |
| SCHEMBL16800528 | 0.92 | HSD17B10 (0.41) | HSD17B10ALDH1A1HTTGAASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098390-A1 | ALBUMIN-BINDING PSMA INHIBITORS | CANCER TARGETED TECHNOLOGY LLC (US) | 2018-05-31 | — | — | WO | disclosed |