SCHEMBL20202980

SCHEMBL20202980

CCc1ccc(CCc2ccc(-c3ccc(C4CCCCC4)cc3F)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.49
APP P05067 3/20 0.49
CYP2C9 P11712 2/20 0.49
FFAR4 Q5NUL3 2/20 0.41
RARB P10826 1/20 0.38
S1PR1 P21453 5/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
FASN P49327 1/20 0.37
S1PR5 Q9H228 4/20 0.37
S1PR4 O95977 1/20 0.37
S1PR3 Q99500 2/20 0.36
CHKA P35790 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
HTR1D P28221 1/20 0.34
PDK2 Q15119 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202981 0.90 CYP3A4 (0.49) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL20202974 0.88 FASN (0.47) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL18558966 0.88 CYP3A4 (0.53) CYP3A4APPCYP2C9FFAR4S1PR1
SCHEMBL18459108 0.88 CYP3A4 (0.53) CYP3A4APPCYP2C9FFAR4S1PR1
SCHEMBL9664291 0.87 FASN (0.38) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL20209858 0.87 FASN (0.38) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL21741417 0.86 CYP3A4 (0.51) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL20202982 0.85 CYP2C9 (0.40) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL9664373 0.85 CYP2C9 (0.40) CYP3A4APPCYP2C9FFAR4RARB
SCHEMBL9662994 0.83 RARB (0.41) CYP3A4APPCYP2C9FFAR4RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed