Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339702 | 0.86 | BTK (0.49) | BTK | |
| SCHEMBL3341753 | 0.79 | BTK (0.41) | BTK | |
| SCHEMBL3346418 | 0.78 | BTK (0.49) | BTK | |
| SCHEMBL3339699 | 0.77 | BTK (0.49) | BTK | |
| SCHEMBL3345671 | 0.76 | BTK (0.47) | BTK | |
| SCHEMBL3347853 | 0.76 | BTK (0.62) | BTK | |
| SCHEMBL23162479 | 0.75 | BTK (0.63) | BTK | |
| SCHEMBL3341834 | 0.75 | BTK (0.45) | BTK | |
| SCHEMBL3342303 | 0.75 | BTK (0.38) | BTK | |
| SCHEMBL174854 | 0.75 | BTK (0.74) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098275-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-31 | — | — | WO | disclosed |