Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 1.00 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23116229 | 0.92 | CYP1A2 (0.85) | CYP1A2ACACB | |
| SCHEMBL26539187 | 0.92 | CYP1A2 (0.85) | CYP1A2ACACB | |
| SCHEMBL31339061 | 0.92 | CYP1A2 (0.85) | CYP1A2ACACB | |
| SCHEMBL23116177 | 0.91 | CYP1A2 (0.82) | CYP1A2ACACB | |
| SCHEMBL30884080 | 0.91 | CYP1A2 (0.82) | CYP1A2ACACB | |
| SCHEMBL23116260 | 0.88 | CYP1A2 (0.78) | CYP1A2ACACB | |
| SCHEMBL22711895 | 0.86 | CYP1A2 (0.76) | CYP1A2SCN5ASCN1ASCN2A | |
| SCHEMBL22712083 | 0.86 | CYP1A2 (0.76) | CYP1A2SCN5ASCN1ASCN2A | |
| SCHEMBL22711945 | 0.86 | CYP1A2 (0.76) | CYP1A2SCN5ASCN1ASCN2A | |
| SCHEMBL34468368 | 0.86 | CYP1A2 (0.76) | CYP1A2SCN5ASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20210188852-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2021-06-24 | — | — | US | disclosed |
| WO-2018098499-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188852-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885ACACB 814/4885SCN5A 8/4885 |
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885ACACB 814/4885SCN5A 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.