Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 4/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203704 | 0.93 | CYP1A2 (0.45) | CYP1A2TNK2SCN5AMETDGAT1 | |
| SCHEMBL26539190 | 0.91 | CYP1A2 (0.44) | CYP1A2TNK2SCN5AMETDGAT1 | |
| SCHEMBL20203907 | 0.89 | CYP1A2 (0.48) | CYP1A2TNK2SCN5AMETDGAT1 | |
| SCHEMBL20204033 | 0.88 | CYP1A2 (0.56) | CYP1A2SCN5AMETDGAT1RIPK1 | |
| SCHEMBL20204039 | 0.88 | CYP1A2 (0.56) | CYP1A2SCN5AMETDGAT1RIPK1 | |
| SCHEMBL20204031 | 0.88 | CYP1A2 (0.56) | CYP1A2SCN5AMETDGAT1RIPK1 | |
| SCHEMBL26539208 | 0.86 | CYP1A2 (0.47) | CYP1A2TNK2SCN5AMETDGAT1 | |
| SCHEMBL26539214 | 0.86 | CYP1A2 (0.47) | CYP1A2TNK2SCN5AMETDGAT1 | |
| SCHEMBL26539218 | 0.86 | CYP1A2 (0.47) | CYP1A2TNK2SCN5AMETDGAT1 | |
| SCHEMBL20203964 | 0.80 | CYP1A2 (0.47) | CYP1A2SCN5AMETDGAT1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098499-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |