Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26539322 | 0.93 | CYP1A2 (0.53) | CYP1A2SCN5ADYRK1AAAK1SCN9A | |
| SCHEMBL20190396 | 0.88 | CYP1A2 (0.54) | CYP1A2SCN5AAAK1MAPK14SCN9A | |
| SCHEMBL20203724 | 0.86 | CYP1A2 (0.48) | CYP1A2SCN5AAAK1MAPK14FYN | |
| SCHEMBL20204047 | 0.86 | CYP1A2 (0.67) | CYP1A2SCN5A | |
| SCHEMBL26539413 | 0.85 | CYP1A2 (0.60) | CYP1A2SCN5ADYRK1ASCN9A | |
| SCHEMBL20203876 | 0.80 | CYP1A2 (0.75) | CYP1A2SCN5ADYRK1AAAK1 | |
| SCHEMBL20203780 | 0.80 | CYP1A2 (0.76) | CYP1A2SCN5ADYRK1AFYN | |
| SCHEMBL26539343 | 0.79 | CYP1A2 (0.48) | CYP1A2SCN5AAAK1MAPK14FYN | |
| SCHEMBL938029 | 0.78 | CYP1A2 (0.70) | CYP1A2SCN5A | |
| SCHEMBL20203811 | 0.76 | CYP1A2 (0.76) | CYP1A2SCN5AAAK1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20210188852-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2021-06-24 | — | — | US | disclosed |
| WO-2018098499-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188852-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885SCN5A 8/4885DYRK1A 4493/4885 |
| US-20230322790-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CYP1A2 1988/4885SCN5A 8/4885DYRK1A 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.