Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.79 |
| ▸ | GRIN2A | Q12879 | 20/20 | 0.79 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637862 | 0.90 | GRIN1 (0.85) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645602 | 0.88 | GRIN1 (1.00) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645922 | 0.87 | GRIN1 (0.79) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16637960 | 0.87 | GRIN1 (0.79) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645478 | 0.86 | GRIN1 (0.77) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16645470 | 0.86 | GRIN1 (0.83) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL17958083 | 0.85 | GRIN1 (0.79) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16637259 | 0.83 | GRIN1 (0.77) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL16636241 | 0.82 | GRIN1 (0.71) | GRIN1GRIN2AGRIA2 | |
| SCHEMBL17958171 | 0.80 | GRIN1 (0.69) | GRIN1GRIN2AGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988400-B2 | Thiazolopyrimidinones and methods of use thereof | GENENTECH, INC. (US) | 2018-06-05 | — | — | US | claimed |