Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861896 | 0.91 | MAPT (0.60) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL10144042 | 0.87 | MEN1 (0.53) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL19255773 | 0.86 | SMN1; SMN2 (0.48) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL20204574 | 0.84 | MAPT (0.52) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL15962311 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL3561212 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL3561214 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL15955781 | 0.81 | MAPT (0.46) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL3562552 | 0.80 | CDC25B (0.48) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL3562547 | 0.80 | CDC25B (0.48) | MEN1KMT2AMAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096510-A1 | HETEROARYLPHENOXY BENZAMIDE KAPPA OPIOID LIGANDS | PFIZER INC. (US) | 2018-05-31 | — | — | WO | disclosed |