Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204635 | 0.92 | CAPN1 (0.48) | CAPN1AHRMEN1KMT2AHTR6 | |
| SCHEMBL21707861 | 0.82 | CAPN1 (0.61) | CAPN1AHRMEN1KMT2AHTR6 | |
| SCHEMBL21707883 | 0.79 | CAPN1 (0.77) | CAPN1MEN1KMT2ATSHR | |
| SCHEMBL21707860 | 0.76 | AHR (0.48) | CAPN1AHRMEN1KMT2AHTR6 | |
| SCHEMBL20204667 | 0.74 | CAPN1 (0.58) | CAPN1MEN1KMT2AGPR84MAPT | |
| SCHEMBL20204872 | 0.74 | MEN1 (0.57) | CAPN1AHRMEN1KMT2AHTR6 | |
| SCHEMBL20204741 | 0.74 | MEN1 (0.57) | CAPN1AHRMEN1KMT2AHTR6 | |
| SCHEMBL20204665 | 0.73 | AHR (0.55) | AHRMEN1KMT2AHTR6GPR84 | |
| SCHEMBL20204738 | 0.70 | AHR (0.51) | AHRMEN1KMT2AHTR6GPR84 | |
| SCHEMBL21707863 | 0.68 | CAPN1 (0.71) | CAPN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097999-A1 | COMPOSITIONS AND METHODS FOR MODULATING PROTEASE ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-31 | — | — | WO | disclosed |