SCHEMBL20204884

SCHEMBL20204884

CC(C)(C)OC(=O)/N=C(/NCCCCCCCCn1ccn(CCCOc2ccc(N/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc2)/c1=N/C(=O)C(F)(F)F)NC(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.38
CA1 P00915 5/20 0.38
CA2 P00918 5/20 0.38
CA9 Q16790 5/20 0.38
EPHX2 P34913 3/20 0.35
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ITK Q08881 1/20 0.34
SUCNR1 Q9BXA5 4/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202394 0.89 CA12 (0.39) CA12CA1CA2CA9SUCNR1
SCHEMBL20036325 0.89 CA12 (0.37) CA12CA1CA2CA9SUCNR1
SCHEMBL18296410 0.89 CA12 (0.37) CA12CA1CA2CA9SUCNR1
SCHEMBL20185032 0.89 CA12 (0.37) CA12CA1CA2CA9SUCNR1
SCHEMBL20207461 0.88 CA12 (0.39) CA12CA1CA2CA9EPHX2
SCHEMBL20202386 0.88 CA12 (0.40) CA12CA1CA2CA9EPHX2
SCHEMBL20036296 0.88 CA12 (0.39) CA12CA1CA2CA9EPHX2
SCHEMBL18296428 0.88 CA12 (0.39) CA12CA1CA2CA9EPHX2
SCHEMBL20185004 0.88 CA12 (0.39) CA12CA1CA2CA9EPHX2
SCHEMBL20202478 0.87 CA12 (0.36) CA12CA1CA2CA9SUCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018097172-A1 PHENYLGUANIDINE COMPOUND AND FUNGICIDE 日本曹達株式会社 2018-05-31 WO disclosed