⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21651945 | 0.81 | — | — | |
| SCHEMBL20069129 | 0.77 | — | — | |
| SCHEMBL20147704 | 0.76 | — | — | |
| SCHEMBL22148508 | 0.74 | — | — | |
| SCHEMBL13389905 | 0.74 | — | — | |
| SCHEMBL16285868 | 0.65 | — | — | |
| SCHEMBL23995442 | 0.65 | — | — | |
| SCHEMBL19756465 | 0.65 | CYP2D6 (0.31) | — | |
| SCHEMBL14508370 | 0.64 | — | — | |
| SCHEMBL24733209 | 0.64 | SLC22A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148445-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ARRAY BIOPHARMA INC. | 2018-05-31 | — | — | US | disclosed |