Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147327 | 0.68 | — | — | |
| SCHEMBL17808532 | 0.63 | KCNH2 (0.31) | — | |
| SCHEMBL19398119 | 0.61 | AXL (0.34) | RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL18805511 | 0.56 | — | — | |
| SCHEMBL15982096 | 0.56 | — | — | |
| SCHEMBL993543 | 0.56 | — | — | |
| SCHEMBL10141701 | 0.56 | — | — | |
| SCHEMBL11963992 | 0.55 | — | — | |
| SCHEMBL16201653 | 0.54 | CDC25A (0.32) | — | |
| SCHEMBL12190580 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |