Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189050 | 0.76 | PTPN11 (0.73) | PTPN11GAAMAPTPKMTLR2 | |
| SCHEMBL20206964 | 0.74 | PTPN11 (0.40) | PTPN11GAAMAPTPKM | |
| SCHEMBL20188864 | 0.71 | TLR2 (0.60) | PTPN11TLR2TLR1TLR6 | |
| SCHEMBL23764872 | 0.71 | SELL (0.39) | GAAMAPT | |
| SCHEMBL20191154 | 0.70 | PTPN11 (0.71) | PTPN11GAAMAPTTLR2TLR1 | |
| SCHEMBL20206969 | 0.70 | PTPN11 (0.46) | PTPN11TLR2TLR1TLR6 | |
| SCHEMBL20206978 | 0.69 | TLR2 (0.67) | PTPN11TLR2TLR1TLR6 | |
| SCHEMBL20187628 | 0.69 | PTPN11 (0.68) | PTPN11MAPT | |
| SCHEMBL20206975 | 0.69 | PTPN11 (0.44) | PTPN11GAATLR2TLR1TLR6 | |
| SCHEMBL20206986 | 0.68 | PTPN11 (0.68) | PTPN11TLR2TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096088-A1 | HALOGENATED BENZOTROPOLONES AS ATG4B INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2018-05-31 | — | — | WO | disclosed |