Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 12/20 | 0.55 |
| ▸ | FYN | P06241 | 2/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208536 | 0.84 | SCN5A (0.60) | SCN5ACYP1A2DYRK1AFYN | |
| SCHEMBL20208538 | 0.84 | SCN5A (0.64) | SCN5ACYP1A2DYRK1AFYN | |
| SCHEMBL937481 | 0.78 | CYP1A2 (0.75) | SCN5ACYP1A2DYRK1ACLK2HASPIN | |
| SCHEMBL23535595 | 0.77 | FYN (0.47) | FYN | |
| SCHEMBL16866295 | 0.76 | FYN (0.59) | DYRK1AFYN | |
| SCHEMBL26539244 | 0.76 | SCN5A (0.50) | SCN5ACYP1A2FYN | |
| SCHEMBL26745677 | 0.75 | DYRK1A (0.83) | DYRK1AFYN | |
| SCHEMBL16866294 | 0.75 | FYN (0.61) | DYRK1AFYN | |
| SCHEMBL937201 | 0.75 | CYP1A2 (1.00) | SCN5ACYP1A2DYRK1A | |
| SCHEMBL20203775 | 0.74 | CYP1A2 (0.76) | SCN5ACYP1A2DYRK1ACLK2HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098500-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |