Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850443 | 0.92 | MEN1 (0.61) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL18281226 | 0.92 | MEN1 (0.61) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL1003435 | 0.92 | MEN1 (0.61) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL24580520 | 0.89 | MEN1 (0.63) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL16945135 | 0.89 | MEN1 (0.58) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL10935584 | 0.89 | MEN1 (0.58) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL10164405 | 0.86 | MEN1 (0.55) | MEN1GAAKMT2ATDP1CTSS | |
| SCHEMBL21518411 | 0.86 | MEN1 (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL3183889 | 0.86 | MEN1 (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL28260257 | 0.85 | MEN1 (0.61) | MEN1GAAKMT2ATDP1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096325-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | Enterprise Therapeutics Limited (GB) | 2018-05-31 | — | — | WO | disclosed |