Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458138 | 0.92 | IDH2 (0.83) | IDH2 | |
| SCHEMBL20210806 | 0.89 | IDH2 (0.85) | IDH2 | |
| SCHEMBL20210798 | 0.89 | IDH2 (0.72) | IDH2 | |
| SCHEMBL20210805 | 0.85 | IDH2 (0.69) | IDH2 | |
| SCHEMBL20210797 | 0.83 | IDH2 (0.68) | IDH2 | |
| SCHEMBL18458151 | 0.83 | IDH2 (1.00) | IDH2 | |
| SCHEMBL18458318 | 0.83 | IDH2 (1.00) | IDH2 | |
| SCHEMBL20210795 | 0.82 | IDH2 (0.72) | IDH2 | |
| SCHEMBL18458303 | 0.81 | IDH2 (0.86) | IDH2 | |
| SCHEMBL18458302 | 0.81 | IDH2 (1.00) | IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330263-A1 | ANTITUMOR COMPOUND TARGETING IDH2 MUTATION AND METHOD OF USE THEREOF | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd (CN) | 2018-06-06 | — | — | EP | disclosed |