Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 10/20 | 0.60 |
| ▸ | IDH1 | O75874 | 13/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557175 | 0.88 | IDH1 (0.64) | IDH2IDH1TP53SMN1; SMN2 | |
| SCHEMBL20210922 | 0.84 | IDH2 (0.70) | IDH2IDH1 | |
| SCHEMBL20210921 | 0.84 | IDH2 (0.75) | IDH2IDH1 | |
| SCHEMBL28565600 | 0.82 | IDH2 (0.53) | IDH2IDH1 | |
| SCHEMBL20210918 | 0.81 | IDH1 (0.79) | IDH2IDH1 | |
| SCHEMBL21573323 | 0.80 | NPSR1 (0.59) | IDH2IDH1TP53SMN1; SMN2 | |
| SCHEMBL18760599 | 0.79 | IDH1 (0.83) | IDH2IDH1 | |
| SCHEMBL18557080 | 0.78 | IDH2 (0.53) | IDH2IDH1 | |
| SCHEMBL16392799 | 0.77 | IDH1 (0.80) | IDH2IDH1 | |
| SCHEMBL21573291 | 0.77 | IDH1 (0.80) | IDH2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307794-A | 1,3, 5-triazine derivatives and methods of use thereof | 正大天晴药业集团股份有限公司 | 2021-08-27 | — | — | CN | disclosed |
| EP-3330258-B1 | 1, 3, 5-TRIAZINE DERIVATIVE AND METHOD OF USING SAME | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-07-14 | — | — | EP | disclosed |
| EP-3330258-B1 | 1, 3, 5-TRIAZINE DERIVATIVE AND METHOD OF USING SAME | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-07-14 | — | — | EP | disclosed |
| CN-107922358-B | 1,3, 5-triazine derivatives and methods of use thereof | 正大天晴药业集团股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| US-10745383-B2 | 1,3,5-triazine derivative and method of using same | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-08-18 | — | — | US | disclosed |
| US-10745383-B2 | 1,3,5-triazine derivative and method of using same | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-08-18 | — | — | US | disclosed |
| US-10654826-B2 | — | — | 2020-05-19 | — | — | US | disclosed |
| US-10654826-B2 | — | — | 2020-05-19 | — | — | US | disclosed |
| EP-3330258-A1 | 1, 3, 5-TRIAZINE DERIVATIVE AND METHOD OF USING SAME | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd (CN) | 2018-06-06 | — | — | EP | disclosed |
| EP-3330258-A1 | 1, 3, 5-TRIAZINE DERIVATIVE AND METHOD OF USING SAME | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd (CN) | 2018-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745383-B2 | 1,3,5-triazine derivative and method of using same | IDH2, IDH3A, IDH1 | IDH2 1/4885IDH1 3/4885TP53 5/4885 |
| US-10654826-B2 | — | IDH2, IDH1, IDH3A | IDH2 1/4885IDH1 2/4885TP53 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.