Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 6/20 | 0.59 |
| ▸ | PPP5C | P53041 | 2/20 | 0.59 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.59 |
| ▸ | NPY4R | P50391 | 1/20 | 0.59 |
| ▸ | PPM1B | O75688 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18235542 | 0.87 | TFPI2 (0.55) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL26377841 | 0.87 | TFPI2 (0.55) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL12390213 | 0.80 | TFPI2 (0.70) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL9880159 | 0.80 | TFPI2 (0.70) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL26377804 | 0.80 | TFPI2 (0.70) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL26377839 | 0.79 | TFPI2 (0.60) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL18235540 | 0.79 | TFPI2 (0.60) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| SCHEMBL18073218 | 0.76 | TFPI2 (0.54) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| Lb-100 SCHEMBL13311584 | 0.75 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RPPM1B | |
| Lb-100 SCHEMBL19512780 | 0.75 | TFPI2 (1.00) | TFPI2PPP5CPPP2CANPY4RPPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988394-B2 | Oxabicycloheptane prodrugs | LIXTE BIOTECHNOLOGY INC. (US) | 2018-06-05 | — | — | US | disclosed |