Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609161 | 0.97 | KCNH2 (0.71) | KCNH2LARS1MAPK14HRH3 | |
| SCHEMBL17233236 | 0.90 | KCNH2 (0.66) | KCNH2LARS1HRH3 | |
| SCHEMBL17233268 | 0.86 | KCNH2 (0.61) | KCNH2LARS1HRH3 | |
| SCHEMBL17233263 | 0.86 | KCNH2 (0.62) | KCNH2LARS1HRH3 | |
| SCHEMBL17233327 | 0.86 | KCNH2 (0.62) | KCNH2LARS1 | |
| SCHEMBL17233333 | 0.85 | KCNH2 (0.67) | KCNH2HRH3 | |
| SCHEMBL17233015 | 0.85 | KCNH2 (0.75) | KCNH2LARS1 | |
| SCHEMBL17232987 | 0.84 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL17232990 | 0.84 | KCNH2 (0.63) | KCNH2LARS1HRH3 | |
| SCHEMBL17233307 | 0.83 | KCNH2 (0.62) | KCNH2LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988361-B2 | Anti-enterovirus 71 thiadiazolidine derivative | JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) | 2018-06-05 | — | — | US | disclosed |