Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.73 |
| ▸ | TTK | P33981 | 7/20 | 0.73 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.73 |
| ▸ | INCENP | Q9NQS7 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16292346 | 0.96 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL20211185 | 0.96 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16292344 | 0.96 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16308711 | 0.96 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16308685 | 0.89 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL20211213 | 0.89 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16296498 | 0.89 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16296497 | 0.89 | TTK (0.80) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16291713 | 0.86 | CYP3A4 (0.71) | CYP3A4TTKAURKBINCENPMAPK1 | |
| SCHEMBL16308703 | 0.85 | CYP3A4 (0.70) | CYP3A4TTKAURKBINCENPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |