Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.55 |
| ▸ | TTK | P33981 | 9/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.55 |
| ▸ | INCENP | Q9NQS7 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217315 | 0.97 | CYP3A4 (0.52) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217632 | 0.96 | CYP3A4 (0.52) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217750 | 0.92 | CYP3A4 (0.67) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217592 | 0.90 | CYP3A4 (0.53) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217603 | 0.89 | CYP3A4 (0.46) | CYP3A4TTKAURKBINCENPSLC5A7 | |
| SCHEMBL20217221 | 0.88 | TTK (0.51) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217450 | 0.88 | CYP3A4 (0.42) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217617 | 0.88 | CYP3A4 (0.49) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217458 | 0.87 | CYP3A4 (0.50) | CYP3A4TTKAURKBINCENPLMNA | |
| SCHEMBL20217573 | 0.86 | CYP3A4 (0.41) | CYP3A4TTKAURKBINCENPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |