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SCHEMBL20218802

SCHEMBL20218802

C=CC(C)(C)CC(=O)NC(CSC/C=C(\C)CC/C=C(\C)CCC=C(C)C)C(C)=O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.57
▸ ALDH1A1 P00352 1/20 0.57
▸ ICMT O60725 14/20 0.49
▸ MEN1 O00255 1/20 0.44
▸ TRPA1 O75762 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ FNTA P49354 1/20 0.43
▸ FNTB P49356 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19868118 0.82 MAPT (0.64) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL17399961 0.81 MAPT (0.63) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL19868120 0.81 MAPT (0.63) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL20218671 0.81 MAPT (0.52) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL13274239 0.80 MAPT (0.62) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL3420506 0.79 MAPT (0.71) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL21697839 0.79 MAPT (0.58) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL3420511 0.79 MAPT (0.71) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL21697780 0.79 MAPT (0.55) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL21697782 0.79 MAPT (0.63) MAPTALDH1A1ICMTMEN1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330252-A2 ISOPRENYL COMPOUNDS AND METHODS THEREOF Signum Biosciences, Inc. (US) 2018-06-06 — — EP disclosed