Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195109 | 1.00 | TLR7 (0.46) | TLR7TLR8KCNH2 | |
| SCHEMBL20413303 | 0.87 | TLR7 (0.37) | TLR7TLR8KCNH2 | |
| SCHEMBL13195694 | 0.87 | TLR7 (0.54) | TLR7TLR8KCNH2 | |
| SCHEMBL20219473 | 0.87 | TLR7 (0.54) | TLR7TLR8KCNH2 | |
| SCHEMBL13195729 | 0.87 | TLR7 (0.54) | TLR7TLR8KCNH2 | |
| SCHEMBL23472404 | 0.87 | TLR7 (0.51) | TLR7TLR8KCNH2 | |
| SCHEMBL19274277 | 0.87 | TLR7 (0.48) | TLR7TLR8KCNH2 | |
| SCHEMBL13195144 | 0.86 | TLR7 (0.63) | TLR7TLR8KCNH2 | |
| SCHEMBL19269139 | 0.86 | TLR7 (0.63) | TLR7TLR8KCNH2 | |
| SCHEMBL13195845 | 0.86 | TLR7 (0.63) | TLR7TLR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |