Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469754 | 0.94 | HTR2A (0.37) | PGK1STK17BSTK17AHTR2ASYK | |
| SCHEMBL20418680 | 0.80 | HTR2A (0.34) | STK17BSTK17AHTR2A | |
| SCHEMBL13195019 | 0.76 | TLR7 (0.46) | — | |
| SCHEMBL13195087 | 0.76 | STK17B (0.41) | STK17BSTK17ASLC29A1 | |
| SCHEMBL23472264 | 0.73 | TLR8 (0.33) | STK17BSTK17ASYK | |
| SCHEMBL15469710 | 0.73 | TLR8 (0.39) | STK17BSTK17AKDM4EALDH1A1HPGD | |
| SCHEMBL21769211 | 0.72 | STK17B (0.32) | STK17BSTK17A | |
| SCHEMBL20219250 | 0.72 | STK17B (0.40) | STK17BSTK17ASLC29A1 | |
| SCHEMBL13195671 | 0.71 | TLR7 (0.39) | ALDH1A1HPGD | |
| SCHEMBL15469708 | 0.71 | TLR8 (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |