Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399686 | 0.96 | — | — | |
| SCHEMBL2487739 | 0.96 | — | — | |
| SCHEMBL4635 | 0.96 | — | — | |
| SCHEMBL907968 | 0.96 | TSHR (0.44) | TSHRLMNAOPRM1CHRM1AKR1A1 | |
| Ammonia Solution, Strong SCHEMBL374068 | 0.92 | — | — | |
| Butane SCHEMBL11462630 | 0.92 | TSHR (0.42) | TSHRLMNAOPRM1CHRM1AKR1A1 | |
| Hydrochloric Acid SCHEMBL6130399 | 0.92 | — | — | |
| Hydrogen Sulfide SCHEMBL5675257 | 0.92 | — | — | |
| Water SCHEMBL3346079 | 0.92 | TSHR (0.42) | TSHRLMNAOPRM1CHRM1AKR1A1 | |
| SCHEMBL8037840 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516579-B1 | NON OZONE DEPLETING AND LOW GLOBAL WARMING POTENTIAL REFRIGERANTS FOR LOW TEMPERATURE REFRIGERATION | RPL HOLDINGS LTD (GB) | 2016-03-02 | — | — | EP | claimed |
| US-9023231-B2 | Non ozone depleting and low global warming potential refrigerants for low temperature refrigeration | RPL HOLDINGS LIMITED (GB) | 2015-05-05 | — | — | US | claimed |
| US-20120312048-A1 | NON OZONE DEPLETING AND LOW GLOBAL WARMING POTENTIAL REFRIGERANTS FOR LOW TEMPERATURE REFRIGERATION | RPL HOLDINGS LIMITED (GB) | 2012-12-13 | — | — | US | claimed |
| EP-2516579-A1 | NON OZONE DEPLETING AND LOW GLOBAL WARMING POTENTIAL REFRIGERANTS FOR LOW TEMPERATURE REFRIGERATION | RPL Holdings Limited (GB) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077088-A1 | NON OZONE DEPLETING AND LOW GLOBAL WARMING POTENTIAL REFRIGERANTS FOR LOW TEMPERATURE REFRIGERATION | RPL HOLDINGS LIMITED (GB) | 2011-06-30 | — | — | WO | claimed |
| CN-1204222-C | Multi-component mixture working medium throttling refrigerant suitable for cryogenic temperature zone | RIKAGAKU KENKYUSHO (CN) | 2005-06-01 | — | — | CN | disclosed |
| CN-1475544-A | Multi-component mixture working medium throttling refrigerant suitable for cryogenic temperature zone | 中国科学院理化技术研究所 | 2004-02-18 | — | — | CN | disclosed |