⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20226907 | 1.00 | — | — | |
| SCHEMBL20223762 | 1.00 | — | — | |
| SCHEMBL20223725 | 0.78 | — | — | |
| SCHEMBL20223746 | 0.78 | — | — | |
| SCHEMBL23736340 | 0.73 | — | — | |
| SCHEMBL13221854 | 0.73 | — | — | |
| SCHEMBL13221866 | 0.73 | — | — | |
| SCHEMBL13221857 | 0.73 | — | — | |
| SCHEMBL20223747 | 0.72 | — | — | |
| SCHEMBL22872633 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358711-B2 | Tetracyclic heterocycle compounds useful as HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2022-06-14 | — | — | US | disclosed |
| US-10829499-B2 | Tetracyclic heterocycle compounds useful as HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2020-11-10 | — | — | US | disclosed |
| US-10479801-B2 | Tetracyclic heterocycle compounds useful as HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2019-11-19 | — | — | US | disclosed |
| US-20190315769-A1 | TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2019-10-17 | — | — | US | disclosed |
| US-20180155365-A1 | TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-06-07 | — | — | US | disclosed |
| US-20180155365-A1 | TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-06-07 | — | — | US | disclosed |