SCHEMBL20224360

SCHEMBL20224360

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)C4(c6ccccc6-c6ccccc6-5)c5ccccc5-c5cc6c(cc54)oc4ccccc46)n3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.37
KMT2A Q03164 8/20 0.36
MAPT P10636 7/20 0.36
MEN1 O00255 6/20 0.36
ALDH1A1 P00352 5/20 0.36
HPGD P15428 5/20 0.36
MAPK1 P28482 1/20 0.35
PDK2 Q15119 3/20 0.34
KDM4E B2RXH2 4/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PGR P06401 1/20 0.33
LMNA P02545 2/20 0.33
ATM Q13315 1/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20224354 0.99 AHR (0.38) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL18156774 0.98 AHR (0.38) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL21887634 0.98 AHR (0.38) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL20224355 0.97 PDK2 (0.35) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL20224415 0.97 AHR (0.38) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL20224267 0.95 AHR (0.38) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL18156766 0.94 AHR (0.39) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL20224270 0.93 KMT2A (0.40) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL20224416 0.93 PDK2 (0.36) AHRKMT2AMAPTMEN1ALDH1A1
SCHEMBL24039489 0.93 MAPT (0.37) AHRKMT2AMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183641-B2 Composition for an organic electronic device and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2021-11-23 US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11183641-B2 Composition for an organic electronic device and organic electronic device using the same ORC3, ZYX, ESR1 AHR 653/4885KMT2A 1063/4885MAPT 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.