SCHEMBL20224499

SCHEMBL20224499

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc5-4)c4ccccc4-c4c3ccc3oc5ccccc5c43)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.34
MEN1 O00255 4/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 3/20 0.34
NTSR1 P30989 1/20 0.34
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
WEE1 P30291 1/20 0.32
GLA P06280 1/20 0.31
PDK2 Q15119 1/20 0.30
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20224485 0.98 KMT2A (0.35) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL18732056 0.95 KMT2A (0.34) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20224478 0.95 WEE1 (0.33) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20224482 0.94 PDK2 (0.33) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL18156761 0.94 WEE1 (0.33) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20224495 0.93 KMT2A (0.32) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20224483 0.93 KMT2A (0.32) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20224497 0.92 PDK2 (0.37) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL24039488 0.92 KMT2A (0.32) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20224491 0.92 PDK2 (0.39) KMT2AMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed
US-20180159044-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-06-07 US disclosed