Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.89 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.78 |
| ▸ | BTK | Q06187 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211600 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2BTK | |
| SCHEMBL18262194 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2BTK | |
| SCHEMBL24027431 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2BTK | |
| SCHEMBL20227880 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2BTK | |
| SCHEMBL16993124 | 0.88 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993269 | 0.85 | FGFR1 (0.79) | FGFR1FGFR2 | |
| SCHEMBL16993270 | 0.85 | FGFR1 (0.79) | FGFR1FGFR2 | |
| SCHEMBL18262246 | 0.85 | FGFR1 (1.00) | FGFR1FGFR2BTK | |
| SCHEMBL18270413 | 0.85 | FGFR1 (1.00) | FGFR1FGFR2BTK | |
| SCHEMBL18262247 | 0.85 | FGFR1 (1.00) | FGFR1FGFR2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | FGFR1, FGFR3, FGFR2 | FGFR1 1/4885FGFR2 3/4885BTK 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.