Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217092 | 1.00 | POLA1 (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL21564172 | 1.00 | POLA1 (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20230410 | 1.00 | POLA1 (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20217039 | 1.00 | POLA1 (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20230417 | 1.00 | POLA1 (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20217041 | 1.00 | POLA1 (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20217025 | 0.91 | PDE5A (0.36) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20217065 | 0.91 | PDE5A (0.38) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL20217096 | 0.90 | PDE5A (0.36) | POLA1POLBPDE5APDE4APDE4B | |
| SCHEMBL26455346 | 0.86 | POLA1 (0.37) | POLA1POLBPDE5APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018099946-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | Universität Bern (CH) | 2018-06-07 | — | — | WO | disclosed |