SCHEMBL20230482

SCHEMBL20230482

c1ccc(-c2nc3cnnc(-n4c5ccccc5c5cc(-n6c7ccccc7c7ccccc76)ccc54)c3nc2-c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.37
RAC2 P15153 1/20 0.37
RAC3 P60763 1/20 0.37
CDC42 P60953 1/20 0.37
RAC1 P63000 1/20 0.37
KDM4E B2RXH2 4/20 0.35
ATM Q13315 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPY5R Q15761 1/20 0.32
KHK P50053 1/20 0.32
ALDH1A1 P00352 3/20 0.31
MAPK1 P28482 2/20 0.31
USP2 O75604 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20230490 0.88 KDM4E (0.37) PDE10ARAC2RAC3CDC42RAC1
SCHEMBL20230480 0.87 KDM4E (0.41) PDE10ARAC2RAC3CDC42RAC1
SCHEMBL20230498 0.81 CYP1A2 (0.36) PDE10ARAC2RAC3CDC42RAC1
SCHEMBL24596554 0.80 KDM4E (0.47) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL20230503 0.80 KDM4E (0.37) PDE10AKDM4EATML3MBTL1KMT2A
SCHEMBL18415423 0.79 HSD17B10 (0.42) PDE10ARAC2RAC3CDC42RAC1
SCHEMBL20230481 0.78 KDM4E (0.36) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL21778276 0.78 KDM4E (0.42) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL24596515 0.78 MEN1 (0.39) PDE10ARAC2RAC3CDC42RAC1
SCHEMBL20813064 0.77 KDM4E (0.50) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10388887-B2 Delayed fluorescence compound for organic EL device and using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-08-20 US disclosed
US-20180159049-A1 DELAYED FLUORESCENCE COMPOUND FOR ORGANIC EL DEVICE AND USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2018-06-07 US disclosed
US-20180159049-A1 DELAYED FLUORESCENCE COMPOUND FOR ORGANIC EL DEVICE AND USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10388887-B2 Delayed fluorescence compound for organic EL device and using the same SLCO4C1, SLCO1A2, SLCO1B1 PDE10A 4362/4885RAC2 4445/4885RAC3 4320/4885
US-20180159049-A1 DELAYED FLUORESCENCE COMPOUND FOR ORGANIC EL DEVICE AND USING THE SAME SLCO4C1, SLCO1A2, SLCO1B1 PDE10A 4362/4885RAC2 4445/4885RAC3 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.