Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 6/20 | 0.43 |
| ▸ | BDNF | P23560 | 3/20 | 0.43 |
| ▸ | PTN | P21246 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
| ▸ | IFNG | P01579 | 1/20 | 0.33 |
| ▸ | PF4 | P02776 | 1/20 | 0.33 |
| ▸ | BMP2 | P12643 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | BMP6 | P22004 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | CCL11 | P51671 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230555 | 0.87 | MDK (0.43) | MDKBDNFPTNF10HPSE | |
| SCHEMBL19599631 | 0.85 | MDK (0.46) | MDKBDNFPTNF10HPSE | |
| SCHEMBL16016954 | 0.84 | CD69 (0.43) | MDKLGALS3LGALS8LGALS4CD69 | |
| SCHEMBL13040929 | 0.83 | MDK (0.48) | MDKBDNFPTNF10LGALS3 | |
| SCHEMBL20230553 | 0.83 | MDK (0.48) | MDKBDNFPTNF10LGALS3 | |
| SCHEMBL12552827 | 0.83 | MDK (0.48) | MDKBDNFPTNF10LGALS3 | |
| SCHEMBL16134317 | 0.81 | MDK (0.47) | MDKBDNFPTNF10HPSE | |
| SCHEMBL14498180 | 0.81 | MDK (0.46) | MDKBDNFPTNF10LGALS3 | |
| SCHEMBL20230556 | 0.80 | MDK (0.45) | MDKBDNFPTNF10HPSE | |
| SCHEMBL25121361 | 0.79 | MAPK1 (0.44) | MDKBDNFPTNF10LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180154005-A1 | CONJUGATES COMPRISING AN GLP-1/GLUCAGON DUAL AGONIST, A LINKER AND HYALURONIC ACID | SANOFI (FR) | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180154005-A1 | CONJUGATES COMPRISING AN GLP-1/GLUCAGON DUAL AGONIST, A LINKER AND HYALURONIC ACID | GLP1R, GIPR, GCGR | MDK 1146/4885BDNF 1454/4885PTN 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.