Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011267 | 1.00 | CRBN (0.59) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL22266409 | 0.99 | CRBN (0.60) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL22266510 | 0.94 | CRBN (0.59) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL22906659 | 0.94 | CRBN (0.59) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL26017917 | 0.94 | CRBN (0.59) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL27098059 | 0.94 | CRBN (0.59) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL29336480 | 0.90 | CRBN (0.58) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL20759719 | 0.90 | CRBN (0.65) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL20133268 | 0.90 | CRBN (0.55) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL21025992 | 0.90 | CRBN (0.55) | CRBNDDB1MAPTALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210227-A | Heterobifunctional molecules as TEAD inhibitors | 基因泰克公司 | 2022-10-18 | — | — | CN | disclosed |
| WO-2018102067-A2 | TAU-PROTEIN TARGETING PROTACS AND ASSOCIATED METHODS OF USE | Arvinas, Inc. (US) | 2018-06-07 | — | — | WO | disclosed |