Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1979118 | 0.99 | HRH3 (0.58) | HRH3GPR119KDM4EALDH1A1HTT | |
| SCHEMBL1978514 | 0.96 | HRH3 (0.64) | HRH3GPR119TBXAS1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL1977490 | 0.95 | HRH3 (0.62) | HRH3GPR119TBXAS1HRH2HRH1 | |
| SCHEMBL4465038 | 0.93 | HRH3 (0.53) | HRH3GPR119KDM4EALDH1A1HTT | |
| SCHEMBL4493848 | 0.91 | HRH3 (0.68) | HRH3GPR119KDM4ETBXAS1HRH2 | |
| SCHEMBL4489369 | 0.91 | HRH3 (0.72) | HRH3GPR119KDM4ETBXAS1HRH2 | |
| Oxalic Acid SCHEMBL3824753 | 0.89 | KDM4E (0.55) | HRH3GPR119KDM4EALDH1A1HTT | |
| SCHEMBL3824760 | 0.89 | HRH3 (0.57) | HRH3GPR119KDM4ETBXAS1HRH2 | |
| Oxalic Acid SCHEMBL4485952 | 0.88 | HRH3 (0.67) | HRH3GPR119KDM4EALDH1A1HTT | |
| SCHEMBL2025810 | 0.88 | HRH3 (0.65) | HRH3KDM4EALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332910-B1 | New derivatives of azabicyclo[3.2.0]hept-3-yl, method for preparing same and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2013-01-30 | — | — | EP | disclosed |
| EP-2332910-A1 | New derivatives of azabicyclo[3.2.0]hept-3-yl, method for preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-06-15 | — | — | EP | disclosed |