Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.57 |
| ▸ | BCR | P11274 | 11/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.57 |
| ▸ | PRKCA | P17252 | 4/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.55 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | ITK | Q08881 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364396 | 0.90 | ABL1 (0.69) | ABL1BCREGFRPRKCASRC | |
| SCHEMBL1550 | 0.90 | ABL1 (0.69) | ABL1BCREGFRPRKCASRC | |
| Water SCHEMBL28827802 | 0.89 | ABL1 (0.68) | ABL1BCREGFRPRKCASRC | |
| Alcohol SCHEMBL28827807 | 0.87 | ABL1 (0.63) | ABL1BCREGFRPRKCASRC | |
| SCHEMBL3064076 | 0.83 | ABL1 (0.66) | ABL1BCREGFRPRKCASRC | |
| SCHEMBL14763670 | 0.83 | ABL1 (0.61) | ABL1BCREGFRPRKCASRC | |
| SCHEMBL13597737 | 0.82 | ABL1 (0.69) | ABL1BCREGFRPRKCAPDGFRA | |
| SCHEMBL3861941 | 0.82 | ABL1 (0.69) | ABL1BCREGFRPRKCASRC | |
| SCHEMBL3222277 | 0.81 | ABL1 (0.52) | ABL1BCREGFRPRKCASRC | |
| SCHEMBL2572266 | 0.81 | ABL1 (0.55) | ABL1BCREGFRPRKCASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333162-A1 | METOD FOR PREPARING N-(2-METHYL-5-NITROPHENYL)-4-(PYRIDIN-3-YL)PYRIMIDIN-2-AMINE | Silesian Catalysts sp. z o.o. (PL) | 2018-06-13 | — | — | EP | disclosed |