Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL7199765 | 0.96 | — | — | |
| Glycine SCHEMBL30336770 | 0.96 | CA4 (0.47) | — | |
| Glycine SCHEMBL15845334 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL3216076 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL20269830 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL1483142 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL15842973 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL3205805 | 0.92 | — | — | |
| Glycine SCHEMBL20239648 | 0.92 | CA4 (0.44) | — | |
| Glycine SCHEMBL20239631 | 0.92 | CA4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018111756-A1 | METAL COMPLEXES | NOVUS INTERNATIONAL INC. (US) | 2018-06-21 | — | — | WO | disclosed |
| US-20180162803-A1 | METAL COMPLEXES | NOVUS INTERNATIONAL, INC. | 2018-06-14 | — | — | US | disclosed |