Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 10/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GRM8 | O00222 | 2/20 | 0.37 |
| ▸ | GRM6 | O15303 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768687 | 0.95 | NSD2 (0.42) | NSD2GRM4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL27608691 | 0.82 | NSD2 (0.39) | NSD2GRM4CYP1A2CYP2C19ALDH1A1 | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL27467083 | 0.80 | — | — | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL21462059 | 0.74 | NSD2 (0.63) | NSD2GRM4CYP1A2CYP2C19ALDH1A1 | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL61082 | 0.74 | — | — | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL3967053 | 0.74 | — | — | |
| SCHEMBL31348874 | 0.74 | NSD2 (0.63) | NSD2GRM4CYP1A2CYP2C19ALDH1A1 | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL1320265 | 0.72 | — | — | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL8881129 | 0.72 | — | — | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL20515161 | 0.72 | NSD2 (0.60) | NSD2GRM4CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10376592-B2 | Stapled acid-sensitive endosome disrupting alginates | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-08-13 | — | — | US | claimed |
| US-20180161441-A1 | STAPLED ACID-SENSITIVE ENDOSOME DISRUPTING ALGINATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2018-06-14 | — | — | US | claimed |
| US-10967066-B2 | Stapled acid-sensitive endosome disrupting alginates | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190307889-A1 | STAPLED ACID-SENSITIVE ENDOSOME DISRUPTING ALGINATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-10-10 | — | — | US | disclosed |
| US-10376592-B2 | Stapled acid-sensitive endosome disrupting alginates | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-08-13 | — | — | US | disclosed |
| US-20180161441-A1 | STAPLED ACID-SENSITIVE ENDOSOME DISRUPTING ALGINATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161441-A1 | STAPLED ACID-SENSITIVE ENDOSOME DISRUPTING ALGINATES | ALG1, ALG8, EEA1 | NSD2 4396/4885GRM4 2285/4885CYP1A2 4883/4885 |
| US-20190307889-A1 | STAPLED ACID-SENSITIVE ENDOSOME DISRUPTING ALGINATES | ALG1, ALG8, EEA1 | NSD2 4396/4885GRM4 2285/4885CYP1A2 4883/4885 |
| US-10967066-B2 | Stapled acid-sensitive endosome disrupting alginates | ALG1, ALG8, EEA1 | NSD2 4396/4885GRM4 2285/4885CYP1A2 4883/4885 |
| US-10376592-B2 | Stapled acid-sensitive endosome disrupting alginates | ALG1, ALG8, EEA1 | NSD2 4396/4885GRM4 2285/4885CYP1A2 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.