Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 18/20 | 0.59 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.53 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20241068 | 0.90 | P2RX4 (0.57) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20258355 | 0.89 | P2RX4 (0.55) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20240937 | 0.86 | P2RX4 (0.59) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20241096 | 0.85 | P2RX4 (0.51) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20258425 | 0.85 | P2RX4 (0.66) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20258418 | 0.84 | P2RX4 (0.59) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20258484 | 0.84 | P2RX4 (0.64) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL20258422 | 0.83 | P2RX4 (0.61) | P2RX4 | |
| SCHEMBL20258431 | 0.83 | P2RX4 (0.61) | P2RX4 | |
| SCHEMBL20241005 | 0.82 | P2RX4 (0.55) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018104305-A1 | FIELD OF APPLICATION OF THE INVENTION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-14 | — | — | WO | claimed |
| WO-2018104305-A1 | FIELD OF APPLICATION OF THE INVENTION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-14 | — | — | WO | disclosed |