SCHEMBL20243249

SCHEMBL20243249

C=C1/C(=C\CO)C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8071841 1.00 STAT3 (0.30) STAT3
SCHEMBL8071839 1.00 STAT3 (0.30) STAT3
SCHEMBL6817670 1.00 STAT3 (0.30) STAT3
SCHEMBL8071840 1.00 STAT3 (0.30) STAT3
SCHEMBL7146669 1.00 STAT3 (0.30) STAT3
SCHEMBL8077670 1.00 STAT3 (0.30) STAT3
SCHEMBL20243244 0.88
SCHEMBL13853996 0.87
SCHEMBL2528390 0.87
SCHEMBL8079278 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180162884-A1 POLYENE COMPOUND, PREPARATION METHOD AND USE THEREOF CHEMVON BIOTECHNOLOGY CO., LTD. (CN) 2018-06-14 US disclosed
US-20180162884-A1 POLYENE COMPOUND, PREPARATION METHOD AND USE THEREOF CHEMVON BIOTECHNOLOGY CO., LTD. (CN) 2018-06-14 US disclosed
US-9994598-B1 Polyene compound, preparation method and use thereof CHEMVON BIOTECHNOLOGY CO., LTD. (CN) 2018-06-12 US disclosed
US-9994598-B1 Polyene compound, preparation method and use thereof CHEMVON BIOTECHNOLOGY CO., LTD. (CN) 2018-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180162884-A1 POLYENE COMPOUND, PREPARATION METHOD AND USE THEREOF PARG, SQLE, PCBP1 STAT3 3735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.