SCHEMBL20243449

SCHEMBL20243449

CC(C)(C)C(=O)OCSP1(=O)OC[C@H]2OC(n3cnc4c(N)ncnc43)C(F)C2OP(=O)(O)OC[C@H]2OC(n3cnc4c(=O)[nH]c(N)nc43)C(O1)C2O

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18937065 1.00 STING1 (0.76) STING1
SCHEMBL18937466 1.00 STING1 (0.76) STING1
SCHEMBL18937463 1.00 STING1 (0.76) STING1
SCHEMBL19185931 0.97 STING1 (0.79) STING1
SCHEMBL22292017 0.97 STING1 (0.79) STING1
SCHEMBL18937063 0.97 STING1 (0.79) STING1
SCHEMBL18937345 0.95 STING1 (0.69) STING1
SCHEMBL18937344 0.95 STING1 (0.69) STING1
SCHEMBL18937346 0.95 STING1 (0.69) STING1
SCHEMBL22292019 0.94 STING1 (0.74) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994607-B2 Compounds GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2018-06-12 — — US disclosed
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