Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.44 |
| ▸ | NMT2 | O60551 | 4/20 | 0.44 |
| ▸ | TLR2 | O60603 | 3/20 | 0.42 |
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20245010 | 0.88 | NMT1 (0.46) | NMT1NMT2TLR2GLP1RSIRT6 | |
| SCHEMBL21778353 | 0.85 | GLP1R (0.47) | NMT1NMT2TLR2GLP1RSIRT6 | |
| SCHEMBL20245007 | 0.84 | GLP1R (0.44) | TLR2GLP1RMEN1KMT2A | |
| SCHEMBL20245033 | 0.77 | MEN1 (0.47) | GLP1RMEN1KMT2A | |
| SCHEMBL20244927 | 0.77 | MEN1 (0.47) | GLP1RMEN1KMT2A | |
| SCHEMBL8116615 | 0.76 | GLP1R (0.58) | NMT1NMT2TLR2GLP1RSIRT6 | |
| SCHEMBL20245017 | 0.76 | MEN1 (0.40) | NMT1NMT2TLR2GLP1RMEN1 | |
| SCHEMBL20244993 | 0.76 | MEN1 (0.43) | NMT1NMT2TLR2GLP1RMEN1 | |
| SCHEMBL20244935 | 0.76 | MEN1 (0.41) | NMT1NMT2TLR2GLP1RMEN1 | |
| SCHEMBL12196488 | 0.75 | TLR2 (0.43) | NMT1NMT2TLR2GLP1RSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041468-B1 | CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-06-13 | — | — | EP | disclosed |