SCHEMBL20247486

SCHEMBL20247486

COC(C)C(C)C(=O)N1C(C)CC[C@H]1I

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.32
PHGDH O43175 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15692151 0.88 PHGDH (0.36) DPP4PHGDH
SCHEMBL19884189 0.88 PHGDH (0.36) DPP4PHGDH
SCHEMBL15038548 0.88 PHGDH (0.36) DPP4PHGDH
SCHEMBL21145954 0.81 DPP4 (0.32) DPP4PHGDH
SCHEMBL18994025 0.78 DPP4 (0.33) DPP4PHGDH
SCHEMBL19527999 0.78 DPP4 (0.33) DPP4PHGDH
SCHEMBL15832339 0.78 DPP4 (0.33) DPP4PHGDH
SCHEMBL22364662 0.73 PEPD (0.36)
SCHEMBL15832343 0.73 ACE (0.34) DPP4
SCHEMBL15832375 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431477-A1 CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2019-01-23 EP disclosed
EP-2907816-B1 Condensed imidazolylimidazoles as antiviral compounds GILEAD PHARMASSET LLC (US) 2018-06-13 EP disclosed