Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592282 | 0.86 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL17715161 | 0.86 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL20212525 | 0.86 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL7730850 | 0.86 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL19853319 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL19853293 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL29015465 | 0.82 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL29015468 | 0.82 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL30402912 | 0.82 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2BTKCYP1A2POLB | |
| SCHEMBL10591305 | 0.81 | HSD17B10 (0.43) | HSD17B10SMN1; SMN2BTKCYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431477-A1 | CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2019-01-23 | — | — | EP | disclosed |
| EP-2907816-B1 | Condensed imidazolylimidazoles as antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-06-13 | — | — | EP | disclosed |