Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 17/20 | 0.40 |
| ▸ | VEGFA | P15692 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048376 | 0.80 | EPAS1 (0.56) | EPAS1VEGFA | |
| SCHEMBL21362881 | 0.71 | EPAS1 (0.40) | EPAS1VEGFA | |
| SCHEMBL18048389 | 0.68 | EPAS1 (0.41) | EPAS1VEGFA | |
| SCHEMBL19858569 | 0.68 | EPAS1 (0.41) | EPAS1VEGFA | |
| SCHEMBL21362932 | 0.68 | EPAS1 (0.41) | EPAS1VEGFA | |
| SCHEMBL19870755 | 0.67 | EPAS1 (0.52) | EPAS1VEGFA | |
| SCHEMBL19870748 | 0.67 | EPAS1 (0.58) | EPAS1VEGFA | |
| SCHEMBL19870752 | 0.65 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL20975862 | 0.65 | VEGFA (0.45) | EPAS1VEGFA | |
| SCHEMBL18049060 | 0.65 | EPAS1 (0.56) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162807-A1 | AROMATIC COMPOUNDS AND USES THEREOF | PELOTON THERAPEUTICS, INC. | 2018-06-14 | — | — | US | disclosed |
| US-20180162807-A1 | AROMATIC COMPOUNDS AND USES THEREOF | PELOTON THERAPEUTICS, INC. | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162807-A1 | AROMATIC COMPOUNDS AND USES THEREOF | HIF1A, HIF1AN, VHL | EPAS1 13/4885VEGFA 419/4885PDK2 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.