SCHEMBL20253293

SCHEMBL20253293

C=C(CO)C(=O)OCCCc1ccc(-c2ccc(C3CCC(CCC)CC3)cc2)cc1F

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
FFAR4 Q5NUL3 3/20 0.35
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
DGAT1 O75907 4/20 0.32
SOAT1 P35610 2/20 0.32
CNR2 P34972 1/20 0.31
CYP3A4 P08684 1/20 0.31
RAB9A P51151 1/20 0.31
P2RY14 Q15391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755070 0.96 RARB (0.35) CYP2C9ALDH1A1LMNAMAPTFFAR4
SCHEMBL19722455 0.95 RARB (0.35) CYP2C9ALDH1A1LMNAMAPTFFAR4
SCHEMBL19722124 0.90 FFAR4 (0.35) FFAR4DGAT1SOAT1
SCHEMBL19722586 0.89 FFAR4 (0.34) CYP2C9FFAR4RARARARBCNR2
SCHEMBL22082297 0.85 POLB (0.38) CYP2C9ALDH1A1LMNAMAPTFFAR4
SCHEMBL19721943 0.85 CNR2 (0.34) CYP2C9ALDH1A1LMNAMAPTCNR2
SCHEMBL19722159 0.84 RARB (0.41) CYP2C9FFAR4RARARARBCYP3A4
SCHEMBL19722448 0.84 RARB (0.41) CYP2C9FFAR4RARARARBCYP3A4
SCHEMBL19722280 0.83 RARB (0.37) CYP2C9FFAR4RARARARBCYP3A4
SCHEMBL19721859 0.82 S1PR1 (0.39) CYP2C9ALDH1A1LMNAMAPTFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3392324-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-12-09 EP disclosed
US-10442992-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-10-15 US disclosed
US-10428275-B2 Method for manufacturing liquid crystal display device and liquid crystal display device JNC CORPORATION (JP) 2019-10-01 US disclosed
US-10385269-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-08-20 US disclosed
US-20190225887-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2019-07-25 US disclosed
US-20180163138-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-06-14 US disclosed
US-20180163138-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-06-14 US disclosed