Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 18/20 | 0.70 |
| ▸ | SCN1A | P35498 | 17/20 | 0.70 |
| ▸ | SCN5A | Q14524 | 16/20 | 0.70 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256614 | 0.85 | SCN8A (0.69) | SCN8ASCN1ASCN5ASCN1BNR1I2 | |
| SCHEMBL20256845 | 0.83 | SCN1A (0.47) | SCN8ASCN1ASCN5ASCN9ASCN1B | |
| SCHEMBL29669044 | 0.82 | SCN8A (1.00) | SCN8ASCN1ASCN5ASCN9ASCN1B | |
| SCHEMBL20237445 | 0.82 | SCN8A (1.00) | SCN8ASCN1ASCN5ASCN9ASCN1B | |
| SCHEMBL20256638 | 0.79 | SCN1A (0.43) | SCN8ASCN1ASCN5ASCN9ASCN1B | |
| SCHEMBL20256317 | 0.77 | SCN1A (0.41) | SCN8ASCN1ASCN5ASCN9A | |
| SCHEMBL20256592 | 0.77 | SCN1A (0.45) | SCN8ASCN1ASCN5ASCN9ASCN1B | |
| SCHEMBL20256808 | 0.77 | SCN1A (0.70) | SCN8ASCN1ASCN5ASCN1BNR1I2 | |
| SCHEMBL19634207 | 0.76 | SCN8A (0.69) | SCN8ASCN1A | |
| SCHEMBL20256532 | 0.76 | SCN8A (0.69) | SCN8ASCN1ASCN5ASCN1BNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |