Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589372 | 1.00 | AKR1B1 (0.35) | AKR1B1AHCYTSHR | |
| SCHEMBL10039901 | 0.85 | — | — | |
| SCHEMBL8745985 | 0.83 | — | — | |
| SCHEMBL19129826 | 0.76 | — | — | |
| SCHEMBL17309109 | 0.74 | AKR1B1 (0.33) | AKR1B1AHCY | |
| SCHEMBL14298212 | 0.73 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL12298284 | 0.73 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL16365849 | 0.73 | AKR1B1 (0.37) | AKR1B1 | |
| SCHEMBL14298204 | 0.73 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL14845625 | 0.73 | AKR1B1 (0.33) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106693-A1 | SYSTEMS AND METHODS FOR ONE-SHOT GUIDE RNA (ogRNA) TARGETING OF ENDOGENOUS AND SOURCE DNA | EDITAS MEDICINE, INC. (US) | 2018-06-14 | — | — | WO | disclosed |