Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.68 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.68 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.68 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.59 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16855712 | 1.00 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL14396708 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL15104667 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL15024041 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL16600538 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL14580470 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL15268090 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL15104665 | 0.91 | SLC28A1 (0.68) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL16855719 | 0.90 | P2RY2 (0.58) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL20149828 | 0.90 | P2RY6 (0.58) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683321-B2 | 4′-or nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180162898-A1 | 4'-OR NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683321-B2 | 4′-or nucleosides for the treatment of HCV | NSUN2, NSUN3, ZC3HAV1 | SLC28A1 8/4885SLC28A2 10/4885SLC29A1 15/4885 |
| US-20180162898-A1 | 4'-OR NUCLEOSIDES FOR THE TREATMENT OF HCV | NSUN2, NSUN3, ZC3HAV1 | SLC28A1 5/4885SLC28A2 10/4885SLC29A1 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.